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  • Itamifast 25mg Fidia Farmaceutici 10 Coated Tablets -32%

Itamifast 25mg Fidia Farmaceutici 10 Coated Tablets

4.69€ 6.90€
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Itamifast 25mg Fidia Pharmaceuticals - Pain Treatment

Active ingredient: Diclofenac potassium

Treatment of mild to moderate pain, such as headache, toothache, muscle and joint pain, back pain and menstrual pain. In children and adolescents it is used for the short-term treatment of pain related to infections with inflammation of the ear, nose or throat, acute postoperative pain after minor surgery.

Dosage and method of use

Itamifast is used according to the following indications

Adults and adolescents over 16 years: 25 mg every 4-6 hours as directed. The highest recommended daily dose is 150 mg
Children and adolescents: Children aged 9 years and older (min.35 kg body weight) and adolescents should be treated with doses up to 2 mg / kg body weight per day in 3 divided doses, depending on the severity of the disorder.

Contraindications

Known hypersensitivity to the active substance or to any of the excipients.
Active gastric or intestinal ulcer, bleeding or perforation.
History of gastrointestinal bleeding or perforation related to previous NSAID therapy.
History of recurrent peptic ulcer / haemorrhage or recurrent peptic ulcer / active bleeding (two or more distinct episodes of ulceration or bleeding)
Last trimester of pregnancy
Conditions that cause an increased tendency to bleed.
Severe liver failure ,.
Hepatic porphyria.
Severe renal insufficiency (glomerular filtration rate> 30 ml / min).
As with other non-steroidal anti-inflammatory drugs (NSAIDs), diclofenac is also contraindicated in patients whose attacks of asthma, urticaria or acute rhinitis are exacerbated by acetylsalicylic acid or other NSAIDs.
Overt congestive heart failure (NYHA class II-IV), ischemic heart disease, peripheral arterial disease and / or cerebral vasculopathy.

Special warnings

Undesirable effects can be minimized by administering the lowest effective dose for the shortest duration necessary to control symptoms

Concomitant use of Itamifast with systemic NSAIDs including selective cyclooxygenase-2 inhibitors should be avoided due to the absence of any evidence demonstrating synergistic benefits and the possibility of additive side effects. For medical reasons, caution is advised in elderly patients. In particular, the use of the lowest effective dose is recommended in frail elderly patients or in those with low body weight. Elderly patients have an increased risk of adverse reactions to NSAIDs in particular gastrointestinal bleeding and perforation which can be fatal. It is also more likely to patients
elderly suffer from renal, cardiac or hepatic impairment.

As with other NSAIDs, allergic reactions may occur in rare cases with diclofenac, including anaphylactic / anaphylactoid reactions without recent exposure.
to the drug. As with other NSAIDs, itamifast may mask the signs and symptoms of infections due to its pharmacodynamic properties.

Pregnancy and breastfeeding

Pregnancy

The systemic concentration of diclofenac, compared with oral formulations, is lower after topical administration. Referring to experience with NSAID treatment for systemic administration, the following is recommended: Inhibition of prostaglandin synthesis may adversely affect pregnancy and / or embryo / fetal development. Results of epidemiological studies suggest an increased risk of miscarriage and cardiac malformation and gastroschisis after use of a prostaglandin synthesis inhibitor in early pregnancy. The absolute risk of cardiac malformations increased from less than 1% to approximately 1.5%.

The risk was believed to increase with dose and duration of therapy. In animals, administration of prostaglandin synthesis inhibitors has been shown to
cause an increase in pre- and post-implantation loss and embryo-fetal mortality. In addition, an increased incidence of various malformations, including cardiovascular, has been reported in animals administered prostaglandin synthesis inhibitors during the organogenetic period. During the first and second trimester of pregnancy, diclofenac should not be administered except in strictly necessary cases. If diclofenac is used by a woman attempting to conceive, or during the first and second trimester of pregnancy, the dose should be kept as low as possible and the duration of treatment as short as possible.

During the third trimester of pregnancy, all prostaglandin synthesis inhibitors can expose the fetus to

Cardiopulmonary toxicity (with premature closure of the arterial duct and pulmonary hypertension);
Renal dysfunction, which can progress to renal failure with oligohydroamnios.

The mother and the newborn, at the end of pregnancy, may be exposed to

  • Possible prolongation of bleeding time, and antiplatelet effect which may occur even at very low doses;
  • Inhibition of uterine contractions resulting in delayed or prolonged labor.

Consequently, diclofenac is contraindicated during the third trimester of pregnancy.

Feeding time

Like other NSAIDs, diclofenac passes into breast milk in small amounts. However, at therapeutic doses of Itami no effects on the suckling child are anticipated. Due to the lack of controlled studies in breastfeeding women, the product should only be used during breastfeeding under the advice of a healthcare professional. In this circumstance, Itaminon should be applied to the breasts of nursing mothers, nor elsewhere on large areas of skin or for an extended period of time.

Expiry and retention

Check the expiration date indicated on the package. The expiry date indicated on the package refers to the product in intact packaging, correctly stored. Store in the original package in order to protect from moisture.

Composition

Active ingredient : 25 mg of potassium diclofenac.
Excipients : Mannitol, Potassium hydrogen carbonate, Sodium lauryl sulfate, Macrogol, Crospovidone, Magnesium stearate.

Format

Pack with 10 coated tablets.

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