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  • Janssen Daktarin 2% Vaginal Cream JANSSEN-CILAG Cream 78g + 16 Applicators -8%

Janssen Daktarin 2% Vaginal Cream JANSSEN-CILAG Cream 78g + 16 Applicators

13.50€ 14.70€
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Janssen Daktarin 2% Vaginal Cream JANSSEN-CILAG - Medical Device

DAKTARIN VAGINAL CREAM is a gynecological product based on miconazole nitrate , which belongs to the therapeutic category of "antifungals", useful for the treatment of genital infections due to fungi.


Daktarin vaginal cream is indicated in case of:

  • vulvovaginal infections due to Candida;
  • Gram positive infection.

Composition and active ingredients


  • Active ingredients: miconazole nitrate
  • Excipients: polyethylene glycol palmito stearate, macrogol, glycerol oleate, liquid paraffin, butylhydroxyanisole, benzoic acid, purified water.

Contraindications and side effects

Daktarin antifungal cream is contraindicated in case of:

  • hypersensitivity to the active substance, to other imidazole derivatives or to any of the listed excipients;
  • infants and children (up to 12 years).

Side effects considered related to the drug are:

  • irritation at the application site with burning and itching,
  • anaphylactic reactions (Very rare),
  • angioedema (Very rare),
  • urticaria (Very rare),
  • contact dermatitis (Very rare),
  • rash (Very rare),
  • vaginal irritation (Very rare)
  • erythema (Very rare).

Method of administration, dosages and posology

For the correct use of DAKTARIN VAGINAL CREAM follow the steps below:

  1. Unscrew the cap, turn it over and pierce the aluminum operculum with the perforating wedge.
  2. Screw the applicator onto the tube instead of the cap.
  3. Slightly press the tube at its lower end to allow the cream to penetrate the applicator. If the plunger offers some resistance, gently pull it out.
  4. Unless prescribed by the treating physician, the applicator must be completely filled.
  5. Remove the applicator from the tube, which must be immediately closed with the cap.
  6. In the lying position, the raised knees spread, gently introduce the applicator into the vagina as deeply as possible. Push the piston completely. Then withdraw the applicator and throw it away.

It is recommended to use the product once a day (in the evening before bedtime) for at least 10 days, even if itching and leucorrhea disappeared after 3 days. In case of no effect, it is advisable to repeat the microbiological tests to confirm the diagnosis. Pediatric population: the safety and efficacy of the product in children and adolescents under the age of 18 years have not yet been established.


Store at a temperature not exceeding 25 °.


  • Should sensitization or an allergic reaction occur, treatment should be discontinued.
  • Adequate therapy should also be followed by the partner if he is infected.
  • The medicine does not stain either skin or clothing.
  • The use of latex condoms or diaphragms during treatment with anti-infective vaginal preparations may decrease the effectiveness of latex contraceptives. Therefore, the cream drug should not be used simultaneously with condoms or latex diaphragm.
  • Severe hypersensitivity reactions, including anaphylaxis and angioedema, have been reported during treatment with the medicinal product or other topical miconazole formulations.
  • It is advisable to apply the following hygienic measures to avoid the sources of infections or reinfections: keep towels and underwear for personal use in order to avoid the infection of other people; regularly change clothing that comes into contact with the infected area to avoid re-infection


Systemically administered miconazole is known to inhibit CYP3A4 / 2C9. Since, following vaginal application, the presence of the drug in the blood is limited, interactions deemed clinically relevant are very rare. However, in patients treated with oral anticoagulants such as warfarin, caution and anticoagulant action should be monitored. The efficacy and undesirable effects of other drugs (e.g. oral hypoglycemic agents and phenytoin), when administered concomitantly with miconazole, may be increased and therefore particular caution is required. Contact with some latex products, such as diaphragm or condom-type contraceptives, and the cream drug, should be avoided, as the latex may be damaged by the emollient base.

Pregnancy and breastfeeding

Although intravaginal absorption is limited, the medicine should only be used in the first trimester of pregnancy if, in the judgment of the physician, the expected benefit outweighs the potential risk. There are no known data on the excretion of miconazole nitrate in breast milk, so great caution should be exercised when administering the drug during lactation.


70 g tube with 16 applicators.