AMFLEE® Combo 50mg / 60mg Cats & Ferrets KRKA 1 Pipette

AMFLEE® Combo 50mg / 60mg Cats and Ferrets KRKA

Pesticides for external use.

ACTIVE PRINCIPLES

Each 0.5 ml pipette contains: Fipronil 50 mg, S-metoprene 60 mg.

EXCIPIENTS

Butylhydroxyanisole (E320), butylhydroxytoluene (E321), povidone (K25), polysorbate 80, ethanol 96%, diethylene glycol monoethyl ether.

INDICATIONS

Cats: To be used for flea infestations only or in association with ticks and / or biting lice. Elimination of fleas (Ctenocephalides spp.). The insecticidal efficacy against new infestations with adult fleas persists for 4 weeks. Prevention of flea multiplication by inhibiting the development of eggs (ovicidal activity), larvae and pupae (larvicidal activity) from eggs laid by adult fleas for six weeks after application. - Elimination of ticks (Ixodes ricinus, Dermacentor variabilis, Rhipicephalus sanguineus). The product has a persistent acaricidal efficacy for up to 2 weeks against ticks. Elimination of biting lice (Felicola subrostratus). The product can be used as part of the treatment strategy for the control of Flea Allergic Dermatitis (FAD), where it has been previously diagnosed by a veterinarian. Ferrets: To be used for flea infestations only or in association with ticks. Elimination of fleas (Ctenocephalides spp.). The insecticidal efficacy against new infestations with adult fleas persists for 4 weeks. Prevention of flea multiplication by inhibiting the development of eggs (ovicidal activity), larvae and pupae (larvicidal activity) from eggs laid by adult fleas. Elimination of ticks (Ixodes ricinus, Dermacentor variabilis, Rhipicephalus sanguineus). The product has a persistent acaricidal efficacy for up to 2 weeks against ticks.

CONTRAINDICATIONS / SECONDARY EFFECT

In the absence of available data, the product should not be used in kittens aged less than 8 weeks and / or weighing less than 1 kg. This product should not be used in ferrets younger than 6 months. Do not use in sick animals (for example, systemic, febrile or convalescent diseases. Do not use in rabbits,
because of the risk of adverse reactions or even death. Do not use in case of hypersensitivity to the active substance or to any of the excipients.

USE / ROUTE OF ADMINISTRATION

Topical.

DOSAGE

For external use only, spot-on use. One 0.5 ml pipette per cat, corresponding to the minimum recommended dose of 5 mg / kg of fipronil and 6 mg / kg of s-metoprene, for topical administration to the skin. In the absence of safety studies, the minimum treatment interval is 4 weeks. One 0.5 ml pipette per ferret, corresponding to the minimum recommended dose of 50 mg / kg of fipronil and 60 mg / kg of S-methoprene, for topical administration to the skin. The minimum treatment interval is 4 weeks. How to use: remove the pipette from the bag. Hold the pipette upright, twist and remove the cap. Invert the cap and replace it on the other end of the pipette. Press and twist the cap to break the seal, then remove the cap from the pipette. Part the fur of the animal on the back of the animal at the base of the neck in front of the shoulder blades until the skin is visible. Place the tip of the pipette on the skin and squeeze the pipette several times to empty the contents completely and directly onto the skin at one point.

STORAGE

Store in the original package to protect it from light and humidity. This veterinary medicinal product does not require any special storage temperatures.

WARNINGS

Fleas present in animals often infest the kennel, blankets and the usual areas where the animal rests such as carpets and furnishing fabrics which, in case of massive infestations and at the beginning of control measures, must be treated with a special insecticide and regularly cleaned with a vacuum cleaner. No information is available on the effect of baths / shampoos on the efficacy of the product in cats and ferrets. However, based on the information available for dogs bathed from 2 days after application of the product, it is not recommended to bathe animals within two days after application of the product. Avoid contact with the animal's eyes. It is important to be sure that the product is applied in an area where the animals cannot lick it and to be sure that the animals do not lick each other following the treatment. Attachment of single ticks can occur. For this reason a transmission of infectious diseases cannot be completely excluded if conditions are favorable. Special precautions to be taken by the person administering the veterinary medicinal product to animals: this product may cause irritation to mucous membranes, skin and eyes. Therefore contact between the product and the mouth, skin and eyes should be avoided. People with known hypersensitivity to insecticides or alcohol should avoid contact with the product. Avoid the content coming into contact with your fingers. If this happens, immediately wash your hands with soap and water. In case of accidental contact with the eyes, wash the eyes immediately and abundantly with clean water. Wash hands after use. In case of accidental ingestion, seek medical advice immediately. Show the package leaflet or the label to the doctor. Do not smoke, drink or eat during application. Treated animals should not be touched until the application site has dried and children should not be allowed to play with treated animals until the application site has dried. It is therefore recommended not to treat animals during the day, but in the evening and not to allow recently treated animals to sleep with their owners, especially children. Overdose: the risk of adverse reactions may 'increase in case of overdose. In cats In the safety studies in the target species, no adverse reactions were observed in cats and kittens aged 8 weeks or older and weighing approximately 1 kg, treated once monthly with 5 times the dose. recommended for 6 consecutive months. Itching may occur after treatment. The application of an overdose of the product can determine the sticky appearance of the hair at the point of application. However, should this occur, it will disappear within 24 hours of application. In ferrets In ferrets 6 months of age or older and treated once every 2 weeks for four treatments, 5 times the recommended dose, weight loss has been observed in some animals.

WAITING TIME

Not relevant.

TARGET SPECIES

Cats, ferrets.

INTERACTIONS

None known.

SIDE EFFECTS

Don't overdose. Cats: Among extremely rare suspected adverse reactions, transient skin reactions at the application site (peeling, local alopecia, pruritus, erythema) and general pruritus or alopecia have been reported after use. Hypersalivation, reversible neurological symptoms (hyperesthesia, depression, nervous symptoms), vomiting and / or respiratory symptoms have also been observed after use. If the animal licks itself, a short period of hypersalivation may be observed due to the nature of the vector.

PREGNANCY AND BREASTFEEDING

Cats: the product can be used during pregnancy. The potential toxicity of the product in kittens aged less than 8 weeks in contact with treated adults is not documented. In this case, particular caution should be used. Ferrets: Laboratory studies in cats have shown no evidence of teratogenic, foetotoxic or maternotoxic effects. The safety of the veterinary medicinal product in pregnant and lactating ferrets has not been established. Use only in accordance with the benefit / risk assessment.

FORMAT

Pack of 1 pipette.