LaxiPEG 97% Macrogol Zambon Powder 200g

Composition

100 g of powder contain: Active ingredient: macrogol 4000 g 97.36 For excipients see par. 6.1.

Excipients

Acesulfame potassium, banana flavor.

Therapeutic indications

Treatment of child constipation.

Contraindications

• Hypersensitivity to the active substance or to any of the excipients. • Laxatives should not be used by people with acute abdominal pain or of unknown origin, nausea or vomiting, marked accentuation or reduction of peristalsis, rectal bleeding. The presence of one or more of these symptoms or signs requires an adequate diagnostic investigation by the doctor in order to exclude one of the pathological conditions that contraindicate the use of laxatives (for example: intestinal obstruction, stenosis or perforation, paralytic ileus, severe inflammatory bowel diseases). • Severe state of dehydration.

Dosage

Children over 8 years of age and weighing more than 20 kg. 2-4 heaped scoops per day (the scoop doses 2.5 g at the notch and 5 g when full). Do not exceed the maximum daily dosage of 20 g of macrogol. Children over 2 years of age and weighing less than 20 kg. The usual starting dose is 0.7 g / kg per day. Table for calculating the dose of Laxipeg in children up to 20 kg.

Body weight (kg)	Daily dose	n. of measuring spoons
6-9	5 g	1
10-12	7.5 g	1 ½
13-16	10 g	2
17-20	12.5 g	2 ½

The indicated dose should be adjusted based on individual response. It is advisable to increase or decrease ½ or 1 scoop with respect to the dose indicated in the table. The correct dose is the minimum sufficient to produce easy evacuation of soft stools. It is advisable to initially use the minimum doses provided. The daily dose can be taken in one or two fractions, away from meals. Sometimes it can take two days (or more) for the desired effect to be achieved. The duration of treatment is limited to 3 months; in any case, the patient must follow the doctor's prescription. The content of one measuring cup (5 g) should be dissolved in at least half a glass of water (about 60 ml). Do not add any other ingredients. It is preferable to drink the entire quantity fairly quickly (within a few minutes) and avoid sipping it for a long time. A diet rich in liquids favors the effect of the medicine.

Warnings and Precautions

Warnings The abuse of laxatives (frequent or prolonged use or with excessive doses), particularly those of contact or stimulants, can cause persistent diarrhea with consequent loss of water, mineral salts (especially potassium) and other essential nutritional factors. In the most severe cases, dehydration or hypokalaemia may develop, which can lead to cardiac or neuromuscular dysfunctions, especially in the case of simultaneous treatment with cardiac glycosides, diuretics or corticosteroids. Caution should be exercised in patients with renal insufficiency or heart failure. In these cases it is advisable to periodically check the levels of serum electrolytes. The abuse of laxatives, especially contact laxatives (stimulant laxatives), can cause addiction (and, therefore, the possible need to gradually increase the dosage), chronic constipation and loss of normal intestinal functions (intestinal atony). LAXIPEG, containing no sugar or polyol, can be taken by diabetic patients or undergoing a galactose-free diet. Precautions for use In-depth diagnostics are necessary when the need for the laxative derives from a sudden change in previous bowel habits (frequency and characteristics of bowel movements) that has lasted for more than two weeks or when the use of the laxative fails to produce effects.

Interactions

Laxatives can reduce the time spent in the intestine and therefore the absorption of other drugs administered simultaneously orally. Therefore, avoid ingesting laxatives and other drugs at the same time: after taking a medicine, leave an interval of at least two hours before taking the laxative. The use of licorice increases the risk of hypokalemia.

Side effects

Gastrointestinal disorders Common: abdominal distension, nausea. Uncommon: abdominal pain, rectal irritation, vomiting. Rare: severe diarrhea. General disorders Very rare: hypersensitivity reactions. They can occur with: itching, rash, hives or edema (swelling, especially in the face or hands; swelling or itching of the lips or throat), difficulty in breathing. In such cases, stop taking the medicine and consult a doctor immediately.

Pregnancy and breastfeeding

There are no adequate and well-controlled studies on the use of the drug in pregnancy or breastfeeding. Therefore, the medicine should only be used in case of need, under the direct supervision of the doctor, after evaluating the expected benefit to the mother in relation to the possible risk to the fetus or infant.

Format

200 g jar.