Neonisidine C 200mg + 300mg + 300mg

Effervescent tablets

Active principles

One effervescent tablet contains: 300 mg acetylsalicylic acid, 200 mg paracetamol, 300 mg ascorbic acid (vitamin C).

Excipients

sodium bicarbonate, citric acid, lactose, lemon flavor, sodium saccharin, polyvinylpyrrolidone, fumaric acid.

Therapeutic indications

Treatment of flu symptoms and cold syndromes. Symptomatic treatment of headache, neuralgia, toothache, menstrual pain and joint pain.

Contraindications

Paracetamol-based products are contraindicated in patients with manifest insufficiency of glucose-6-phosphate dehydrogenase and in those suffering from severe haemolytic anemia. Severe hepatocellular insufficiency. Known individual hypersensitivity to the product. Gastropathies (e.g. gastroduodenal ulcer). Established tendency to haemorrhages. Asthma.

Dosage

1 to 4 effervescent tablets of Neo-Nisidin C per day DO NOT EXCEED THE RECOMMENDED DOSES: in particular elderly patients should follow the minimum dosages indicated above. Neo-Nisidina C must always be dissolved in ½ glass of water before use. The product must be taken on a full stomach. In children under the age of 12, the product should only be administered on medical prescription.

Warnings and Precautions

After three days of use at the maximum dose or after 5-7 days of continuous use, consult your doctor. In addition, the doctor should be consulted by patients with chronic or recurrent gastric or intestinal disorders or impaired renal function. Administer with caution in subjects with renal or hepatic insufficiency. During treatment with paracetamol, before taking any other drug, check that it does not contain the same active ingredient, as serious adverse reactions can occur if paracetamol is taken in high doses. Instruct the patient to contact the physician before associating any other medication. See also the heading “Interactions”. High or prolonged doses of the product can cause high-risk liver disease and even serious changes in the kidney and blood. In case of viral diseases, such as flu or chickenpox, consult your doctor before administering the product to children; if prolonged vomiting and profound drowsiness occur during treatment, discontinue administration. In rare cases of allergic reactions, administration should be discontinued. In the case of a sodium-free or low-sodium regimen, it should be noted that each Neo-Nisidina C tablet contains about 440 mg of sodium. With regard to vitamin C, at higher doses than those recommended, headache and gastrointestinal disorders have been reported; moreover it can interfere, at high doses, on the results of some diagnostic tests (in particular the search for glucose in the urine by non-specific means). Preoperative use can hamper intraoperative haemostasis. KEEP THE MEDICINAL PRODUCT OUT OF THE REACH OF CHILDREN

Interactions

Use with extreme caution and under strict control during chronic treatment with drugs that can determine the induction of hepatic monooxygenases or in case of exposure to substances that can have this effect (for example rifampicin, cimetidine, antiepileptics such as glutethimide, phenobarbital, carbamazepine) . The administration of paracetamol can interfere with the determination of uricaemia (by the phosphotungstic acid method) and with that of blood glucose (by the glucose-oxidase-peroxidase method). The use of the product is not recommended if the patient is being treated with other anti-inflammatories. The drug can interact with anticoagulants, uricosurics, hypoglycemic sulfonylureas.

Side effects

Skin reactions of various types and severities have been reported with the use of paracetamol including cases of erythema multiforme, Stevens-Johnson syndrome and epidermal necrolysis. Hypersensitivity reactions such as angioedema, larynx edema, anaphylactic shock have been reported. In addition, the following undesirable effects have been reported: thrombocytopenia, leukopenia, anemia, agranulocytosis, liver function abnormalities and hepatitis, kidney disorders (acute renal failure, interstitial nephritis, haematuria, anuria), gastrointestinal reactions and dizziness. In case of overdosing, due to the presence of paracetamol, hepatic cytolysis can be caused, which can evolve towards massive and irreversible necrosis. Due to the presence of acetylsalicylic acid, otovestibular disorders (humming, etc.), haemorrhagic phenomena (epistaxis, gingivorrhagia, etc.), delay in childbirth and reduction in platelet counts may also occur.

Pregnancy and breastfeeding

For use in pregnancy consult your doctor. Do not use in the last three months of pregnancy unless the use is specifically prescribed by the doctor.