Sandoz

Lactulose Sandoz 66.7% Syrup

Treatment of occasional constipation

Composition

66.7% syrup, 180 ml bottle 100 ml of syrup contain: Active ingredient: 66.7 g Lactulose.

Excipients

Syrup: sorbic acid; purified water.

Therapeutic indications

Short-term treatment of occasional constipation. Adults: occasional constipation; adjuvant in intestinal bacterial diseases caused by coliform germs (Salmonella, Shigella, etc.). Children and infants: constipation; treatment of putrefactive syndromes, due to eating disorders; as a corrective to the infant's diet, especially in the transition from maternal to artificial breastfeeding.

Contraindications

Hypersensitivity to the active substance or to any of the excipients. Laxatives are contraindicated in subjects with acute abdominal pain or of unknown origin, nausea or vomiting, intestinal obstruction or stenosis, rectal bleeding of unknown origin, severe dehydration. Contraindicated in subjects with galactosemia. Generally contraindicated during pregnancy and lactation (see p. 4.6). Generally contraindicated in pediatric age (see p. 4.4).

Dosage

Adults: the average daily dosage is 10-15 g in two doses. This dosage can be doubled or halved depending on the individual response or clinical picture. Children: from 2.5 to 10 g / day, even in a single administration, depending on the age and severity of the case. Infants: on average 2.5 g per day. The correct dose is the minimum sufficient to produce easy evacuation of soft stools. It is advisable to initially use the minimum doses provided. When necessary, the dose can then be increased, but without ever exceeding the maximum indicated. Take preferably in the evening. Laxatives should be used as infrequently as possible and for no more than seven days. Use for longer periods of time requires a doctor's prescription after adequate evaluation of the individual case. Swallow with an adequate amount of water (a large glass). A diet rich in liquids favors the effect of the medicine.

Warnings and Precautions

Warnings Lactulose is absorbed to a very small extent and has no caloric value. However Lattulosio Sandoz contains in addition to lactulose also galactose, lactose and small quantities of other sugars. This must be taken into account in the treatment of diabetic patients and in patients on low calorie diets. The abuse of laxatives (frequent or prolonged use or with excessive doses) can cause persistent diarrhea with consequent loss of water, mineral salts (especially potassium) and other essential nutritional factors. In severe cases, the onset of dehydration or hypokalemia is possible, which can lead to cardiac or neuromuscular dysfunctions, especially in the case of simultaneous treatment with cardiac glucosides, diuretics or corticosteroids. The abuse of laxatives, especially contact laxatives (stimulant laxatives), can cause addiction (and, therefore, the possible need to gradually increase the dosage), chronic constipation and loss of normal intestinal functions (intestinal atony). Precautions for use Do not use the drug if abdominal pain, nausea and vomiting are present. If constipation is persistent, consult a doctor. In patients presenting with disorders caused by excessive intestinal meteorism it is advisable to start treatment with the minimum doses indicated; these doses can be gradually increased in relation to the patient's response. In children under the age of 12, the medicine can only be used after consulting your doctor. The treatment of chronic or recurrent constipation always requires the intervention of the doctor for the diagnosis, the prescription of drugs and the surveillance during the course of therapy. Consult your doctor when the need for the laxative derives from a sudden change in previous bowel habits (frequency and characteristics of bowel movements) lasting more than two weeks or when the use of the laxative fails to produce effects. It is also advisable for elderly people or those in poor health to consult their doctor before using the medicine.

Interactions

Broad-spectrum antibacterial agents, administered orally at the same time as lactulose, can reduce degradation, limiting the possibility of acidification of the intestinal contents and consequently therapeutic efficacy. Laxatives can reduce the time spent in the intestine, and therefore the absorption, of other drugs administered simultaneously orally. Therefore, avoid ingesting laxatives and other drugs at the same time: after taking a medicine, leave an interval of at least 2 hours before taking the laxative.

Side effects

Occasionally: isolated cramping pains or abdominal colic, more frequent in cases of severe constipation. Occasionally: flatulence.

Pregnancy and breastfeeding

There are no adequate and well-controlled studies on the use of the drug in pregnancy or breastfeeding. Therefore, the medicine should only be used in case of need, under the direct supervision of the doctor, after evaluating the expected benefit to the mother in relation to the possible risk to the fetus or infant.

Format

180ml bottle